Thin Layer Identification of Jiedu Shengxue Granules and Determination of Notoginsenoside R1 Content
刊名 Medicinal Plant
作者 Zhenying FU, Bing QING, Yinghong HUANG, Xianyi SHI, Meiyan QIU, Xian PENG, Jiangcun WEI, Fengzhen LI, Wen ZHONG
作者单位 Guangxi International Zhuang Medical Hospital
DOI 10.19601/j.cnki.issn2152-3924.2024.01.018
年份 2024
刊期 1
页码 71-74
关键词 Jiedu Shengxue granules, Thin layer identification, Notoginsenoside R1, Quality standard
摘要 [Objectives] To establish the quality standard of hospital preparation Jiedu Shengxue granules. [Methods] Scleromitrion diffusum and Prunella vulgaris in Jiedu Shengxue granules were qualitatively identified by thin layer chromatography (TLC). A high performance liquid chromatography (HPLC) was established to determine the content of notoginsenoside R1 in the granule. [Results] The traditional Chinese medicinal materials in Jiedu Shengxue granules could be identified by TLC, and the characteristic spots were stable and clear. Notoginsenoside R1 had a good linear relationship in the range of 10.45-104.5 μg/mL, with an average recovery of 98.52% and RSD=2.36%. [Conclusions] TLC and HPLC, as the quality control methods of Jiedu Shengxue granules, have high accuracy and good repeatability, which lays a foundation for the quality control of this mixture.