Antioxidant and Hypoglycemic Ability of Ardisia gigantifolia Stapf Parts
刊名 Medicinal Plant
作者 Chaohao GU, Shihao LIANG, Yuexuan WU, Zhiren YAO, Jiaojiao LI, Kaimei ZHU
作者单位 Guilin Medical University; Second Affiliated Hospital of Guilin Medical University
DOI 10.19601/j.cnki.issn2152-3924.2024.01.023
年份 2024
刊期 1
页码 88-91
关键词 Ardisia gigantifolia Stapf, Antioxidants, Free radicals, Hypoglycemic effect
摘要 [Objectives] To study the antioxidant and hypoglycemic effects of different parts of Ardisia gigantifolia Stapf. [Methods] The hydroxyl radical scavenging activity, DPPH radical scavenging activity and total antioxidant capacity of ABTS of 75% ethanol extract of A. gigantifolia Stapf and the petroleum ether, ethyl acetate, n-butanol, chloroform and aqueous extract were measured with Vc as positive control. At the same time, acarbose was used as reference substance to determine the inhibitory effect of each polar site on α-glucosidase. [Results] All parts of A. gigantifolia Stapf had antioxidant activity, among which ethyl acetate had the strongest antioxidant activity, and the scavenging rate of hydroxyl radical and DPPH radical was higher than that of positive control. The results showed that petroleum ether, ethyl acetate and chloroform had a good inhibitory effect on α-glucosidase (better than acarbose). [Conclusions] The ethyl acetate part of A. gigantifolia Stapf had the best antioxidant activity and inhibitory effect on α-glucosidase. It provides a basis for further research and development of A. gigantifolia Stapf.