| 摘要 |
[Objectives] To observe the effect of Jianpi Xiaowei Decoction on gastric function and quality of life in elderly patients with chronic atrophic gastritis (CAG) of liver-stomach heat stagnation type. [Methods] Seventy-two elderly patients with CAG of liver-stomach stagnation-heat type were randomly divided into study group and control group. The two groups were treated with Jianpi Xiaowei Decoction and Rabeprazole Enteric-coated Tablets respectively. The curative effect of TCM syndromes, serum pepsinogen I and II (PG-I and PG-II), gastrin-17 (G-17) and quality of life (SF-36 table) scores of gastric function indicators before and after treatment were observed. [Results] After treatment, the total effective rate of the study group was 97.22% (35/36), which was significantly higher than that of the control group 77.78% (28/36) (P<0.05). Before treatment, there was no significant difference in the levels of gastric function indicators between the two groups (P>0.05). After treatment, the indicators of the study group were significantly lower than those of the control group (t=12.239, 6.010, 5.928, 10.420, P<0.05). Before treatment, there was no significant difference in SF-36 scores between the two groups (P>0.05). After treatment, the SF-36 scores in the study group were significantly lower than those in the control group (t=3.520, 10.335, 11.300, 9.693, P<0.05). [Conclusions] Jianpi Xiaowei Decoction can achieve significant curative effect in the treatment of CAG with liver and stomach stagnation heat type in the elderly, and can significantly improve the key gastrointestinal hormone levels and quality of life of elderly patients. It is worthy of promotion in the same clinical cases. |
