ICP-MS Analysis of Inorganic Elements in Astragalus membranaceus from Gansu Province
刊名 Medicinal Plant
作者 Juandi WANG, Zhiqiang ZHANG, Yifan YU, Xiao MA, Ruifeng YANG, Yuanjun LANG, Ruijuan ZHU
作者单位 Gansu Institute for Drug Control; NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine; Anqiu People’s Hospital; Shandong Vocational Animal Science and Veterinary College
DOI 10.19601/j.cnki.issn2152-3924.2025.03.002
年份 2025
刊期 3
页码 5-9,14
关键词 ICP-MS, Astragalus membranaceus, Geographical origin, Inorganic elements, Principal component analysis, Cluster analysis
摘要 [Objectives] To investigate the content and distribution of inorganic elements in Astragalus membranaceus sourced from various regions in Gansu Province. [Methods] 28 batches of A. membranaceus samples were collected and subsequently digested using the Multiwave 7000 super microwave digestion system. The contents of aluminum (Al), barium (Ba), beryllium (Be), cobalt (Co), chromium (Cr), iron (Fe), gallium (Ga), magnesium (Mg), manganese (Mn), nickel (Ni), antimony (Sb), tin (Sn), strontium (Sr), titanium (Ti), thallium (Tl), vanadium (V), and zinc (Zn) were quantified utilizing a PerkinElmer 2000 inductively coupled plasma mass spectrometer. Principal component analysis was performed utilizing SPSS 25.0 to identify the distinctive characteristic elements of A. membranaceus. Additionally, systematic cluster analysis was conducted using these characteristic elements as variables to investigate the relationship between the primary inorganic elements and the geographical origin of A. membranaceus. [Results] 17 inorganic elements were identified in A. membranaceus specimens collected from Gansu Province, with characteristic elements including Ba, Co, Fe, Ga, Mn, Zn, and Sn. The contents of inorganic elements in various sources of A. membranaceus exhibited significant variability and demonstrated distinct clustering characteristics. [Conclusions] A. membranaceus, originating from Gansu Province, exhibits a high content of inorganic elements. However, variations in ecological environments can lead to differences in the specific inorganic elements that are enriched. This study aims to provide a reference for the further development and application of A. membranaceus.